Skin necrosis complicated by warfarin-induced protein S deficiency
نویسندگان
چکیده
منابع مشابه
Warfarin-Induced Skin Necrosis
Warfarin-induced skin necrosis is an infrequent complication occurring in individuals under warfarin treatment who have a thrombophilic history or after administration of large loading doses of warfarin particularly without simultaneous initial use of heparin. A 62-year-old lady developed skin necrosis 4 days after initiating warfarin therapy of 5 mg daily without initial co-administration of h...
متن کاملWarfarin-induced skin necrosis of the eyelids.
Skin necrosis is a rare complication of warfarin therapy that occurs between the third and 10th days of treatment. The pathogenesis of warfarin-induced skin necrosis is attributable to the emergence of a transient hypercoagulable state. The condition most commonly involves skin areas with abundant subcutaneous adipose tissue such as the breasts, buttocks, abdomen, thighs, and the extremities. W...
متن کاملType I protein S deficiency and skin necrosis.
A kindred with Type I protein S deficiency is described in which the index case developed skin necrosis during induction of oral anticoagulant therapy for deep venous thrombosis. Two other family members with protein S deficiency have been detected, and demonstrate the clinical variability of this condition.
متن کاملWarfarin-induced skin necrosis following heparin-induced thrombocytopenia.
Anticoagulants, such as heparin and warfarin, are commonly used in the treatment and prevention of thromboembolic events. The risk of developing warfarin-induced skin necrosis (WISN) with warfarin is reported to be <1%. However, the risk of WISN may be increased with the initiation of warfarin in the setting of heparin-induced thrombocytopenia and thrombosis syndrome (HITT). WISN can lead to ca...
متن کاملwarfarin-induced skin necrosis in patients with low protein c levels
warfarin-induced skin necrosis (wisn) is a rare complication of anticoagulant therapy associated with a high incidence of morbidity and mortality requiring immediate drug cessation. at particular risk are those with various thrombophilic abnormalities, especially when warfarinisation is undertaken rapidly with large loading doses of warfarin. cutaneous findings include petechiae that progress ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Formosan Medical Association
سال: 2014
ISSN: 0929-6646
DOI: 10.1016/j.jfma.2012.09.005